Sample Questions and Answers
What is percutaneous administration?
a) Administration of medication through the skin or mucous membranes
b) Administration of medication through injection
c) Administration of medication via the oral route
d) Administration of medication via inhalation
Answer: a) Administration of medication through the skin or mucous membranes
Which of the following is a percutaneous route?
a) Oral tablets
b) Transdermal patches
c) Intravenous injection
d) Subcutaneous injection
Answer: b) Transdermal patches
What is the primary advantage of transdermal drug administration?
a) Immediate effect
b) Easy to adjust dose
c) Avoids first-pass metabolism
d) High patient discomfort
Answer: c) Avoids first-pass metabolism
Which of the following is NOT a method of percutaneous administration?
a) Sublingual tablet
b) Nasal spray
c) Eye drops
d) Intramuscular injection
Answer: d) Intramuscular injection
Which factor can significantly affect drug absorption through the skin?
a) Skin hydration
b) Patient age
c) Type of medication
d) All of the above
Answer: d) All of the above
Where should a transdermal patch generally be applied?
a) On hairy areas of the body
b) On broken skin
c) On clean, dry, and intact skin
d) Near open wounds
Answer: c) On clean, dry, and intact skin
Which of the following is an example of a topical medication?
a) Antibiotic ointment
b) Oral suspension
c) Insulin injection
d) Sublingual nitroglycerin
Answer: a) Antibiotic ointment
What precaution should a nurse take when applying topical medication?
a) Use bare hands to apply medication
b) Apply to an area larger than prescribed
c) Wear gloves to prevent self-exposure
d) Allow medication to dry before covering
Answer: c) Wear gloves to prevent self-exposure
What is the purpose of occlusive dressings in percutaneous administration?
a) To reduce absorption
b) To enhance drug penetration
c) To replace medication
d) To decrease skin irritation
Answer: b) To enhance drug penetration
Which medication is commonly administered through a transdermal patch?
a) Metformin
b) Nitroglycerin
c) Insulin
d) Warfarin
Answer: b) Nitroglycerin
What should the nurse document after administering a topical medication?
a) Time and site of application
b) Expiration date of medication
c) Manufacturer’s name
d) Method of application
Answer: a) Time and site of application
How should a nitroglycerin ointment be applied?
a) Rub into the skin
b) Apply using an applicator paper
c) Apply to the mucous membrane
d) Inject under the skin
Answer: b) Apply using an applicator paper
Which instruction should be given to a patient using a transdermal patch?
a) Avoid bathing while wearing the patch
b) Rotate the patch application site
c) Always apply the patch in the same area
d) Remove the patch every two days
Answer: b) Rotate the patch application site
What is the primary purpose of sublingual medication administration?
a) Enhance taste
b) Prolong absorption time
c) Bypass digestive enzymes
d) Increase drug metabolism
Answer: c) Bypass digestive enzymes
What is a common complication of percutaneous drug administration?
a) Systemic toxicity
b) Skin irritation
c) Hypoglycemia
d) Cardiac arrest
Answer: b) Skin irritation
How should eye drops be administered to avoid contamination?
a) Touch the dropper to the eye
b) Drop directly on the cornea
c) Avoid contact between dropper and eye
d) Place drops in the nasal corner
Answer: c) Avoid contact between dropper and eye
What is the correct sequence for administering ear drops to an adult?
a) Pull the earlobe downward
b) Pull the pinna upward and back
c) Tilt the head sideways toward the treated ear
d) Insert a cotton swab after application
Answer: b) Pull the pinna upward and back
What type of medication is commonly used for percutaneous absorption testing?
a) Antihistamines
b) Corticosteroids
c) Antibiotics
d) Allergens
Answer: d) Allergens
What is the proper method for applying medicated powders?
a) Sprinkle directly onto wet skin
b) Spread evenly over dry, clean skin
c) Rub into the skin thoroughly
d) Apply to moist skin areas only
Answer: b) Spread evenly over dry, clean skin
Which nursing action is appropriate for administering a nasal spray?
a) Position the patient supine
b) Tilt the head forward slightly
c) Insert the spray tip into the nose and point upward
d) Avoid breathing during administration
Answer: b) Tilt the head forward slightly
What is the purpose of buccal administration?
a) Rapid absorption through mucosa
b) Delayed release of medication
c) Limited systemic effects
d) Reduced side effects
Answer: a) Rapid absorption through mucosa
Which of the following medications is typically administered via buccal route?
a) Aspirin
b) Lozenges
c) Insulin
d) Oral antibiotics
Answer: b) Lozenges
How long should a patient keep their mouth closed after applying a sublingual tablet?
a) 1 minute
b) 5 minutes
c) 10 minutes
d) Until the tablet dissolves completely
Answer: d) Until the tablet dissolves completely
Which statement is true about transdermal administration?
a) It provides a rapid onset of action
b) It requires frequent reapplication
c) It offers sustained drug release
d) It is not suitable for lipid-soluble drugs
Answer: c) It offers sustained drug release
How should a nurse apply medicated lotion?
a) Rub vigorously into the skin
b) Pat gently onto the skin
c) Cover with an airtight dressing
d) Apply over existing medication
Answer: b) Pat gently onto the skin
Which route of percutaneous medication administration is used for respiratory disorders?
a) Topical
b) Inhalation
c) Sublingual
d) Transdermal
Answer: b) Inhalation
Which of the following can enhance the absorption of percutaneous medications?
a) Increased skin thickness
b) Dry, cracked skin
c) Warmth and moisture
d) Reduced circulation
Answer: c) Warmth and moisture
What should a nurse do before applying a new transdermal patch?
a) Apply it over the previous patch
b) Clean the area with alcohol
c) Remove the old patch and cleanse the skin
d) Place the new patch near the old one
Answer: c) Remove the old patch and cleanse the skin
How should ointments be applied to wounds?
a) Directly from the tube
b) Using a sterile applicator
c) With bare hands
d) Onto dirty wounds
Answer: b) Using a sterile applicator
Why is it essential to assess skin integrity before applying topical medication?
a) To minimize drug absorption
b) To prevent infection or irritation
c) To ensure medication is ineffective
d) To avoid drug resistance
Answer: b) To prevent infection or irritation
What should a nurse assess before applying a topical medication?
a) The patient’s diet
b) Skin condition and integrity
c) Blood glucose level
d) Muscle tone
Answer: b) Skin condition and integrity
Which of the following is a common site for a transdermal patch?
a) The soles of the feet
b) The abdomen
c) The inner elbow
d) The upper chest or back
Answer: d) The upper chest or back
What is the purpose of cleaning the skin before applying a topical medication?
a) To reduce medication absorption
b) To prevent infection
c) To create a barrier for the drug
d) To cool the skin
Answer: b) To prevent infection
Which of the following is an example of a medication delivered via percutaneous absorption?
a) Heparin
b) Nicotine patch
c) Amoxicillin tablet
d) Furosemide injection
Answer: b) Nicotine patch
Which route is NOT considered percutaneous?
a) Rectal suppository
b) Ophthalmic drops
c) Intradermal injection
d) Vaginal cream
Answer: c) Intradermal injection
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