NCLEX Respiratory System Disorders Questions and Answers

155 Questions and Answers

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Master the complexities of respiratory care with this focused set of NCLEX Respiratory System Disorders Questions and Answers. Designed specifically for nursing students preparing for the NCLEX, this practice exam provides an in-depth review of key concepts and clinical applications related to respiratory health.

This expertly developed resource includes a wide range of practice questions covering:

  • Common respiratory conditions: asthma, COPD, pneumonia, tuberculosis, pleural effusion, and pulmonary embolism

  • Respiratory assessment techniques: breath sounds, oxygen saturation, chest expansion, and ABG interpretation

  • Priority nursing interventions for impaired gas exchange, ineffective airway clearance, and respiratory distress

  • Pharmacologic management: bronchodilators, corticosteroids, mucolytics, and oxygen therapy

  • Ventilator care and nursing responsibilities in mechanical ventilation

  • Nursing responsibilities in chest tube management

  • Patient education on respiratory therapy, breathing exercises, and smoking cessation

  • Emergency interventions for acute respiratory failure and ARDS

  • Nursing care plans and discharge planning for chronic respiratory diseases

Each question is followed by a clear, evidence-based rationale to enhance critical thinking and reinforce learning.

Ideal for NCLEX review sessions, clinical prep, or independent study, this exam provides high-yield practice that aligns with the test blueprint and real-world nursing scenarios.

Sample Questions and Answers

Which of the following is the primary function of the respiratory system?

Transport of nutrients
B. Gas exchange
C. Regulation of electrolytes
D. Blood circulation
Answer: B. Gas exchange

A patient with chronic obstructive pulmonary disease (COPD) is most likely to exhibit which of the following symptoms?

Sudden chest pain
B. Productive cough and dyspnea
C. Hemoptysis
D. Bradypnea
Answer: B. Productive cough and dyspnea

Which of the following is a priority intervention for a patient experiencing an asthma attack?

Administer a corticosteroid
B. Place the patient in a supine position
C. Administer a short-acting bronchodilator
D. Initiate chest physiotherapy
Answer: C. Administer a short-acting bronchodilator

A patient with pneumonia is experiencing difficulty breathing. What is the best position to improve oxygenation?

Supine
B. Prone
C. High Fowler’s
D. Trendelenburg
Answer: C. High Fowler’s

What is the hallmark sign of acute respiratory distress syndrome (ARDS)?

Wheezing
B. Hypoxemia unresponsive to oxygen therapy
C. Hypercapnia
D. Pleural effusion
Answer: B. Hypoxemia unresponsive to oxygen therapy

A nurse is educating a patient about using a metered-dose inhaler. What is the correct technique?

Exhale completely, press the inhaler, and inhale deeply
B. Press the inhaler and exhale quickly
C. Inhale deeply and press the inhaler simultaneously
D. Hold the inhaler 2 feet away from the mouth and inhale slowly
Answer: A. Exhale completely, press the inhaler, and inhale deeply

Which of the following diagnostic tests is the gold standard for diagnosing pulmonary embolism?

Chest X-ray
B. D-dimer test
C. Ventilation-perfusion (V/Q) scan
D. CT pulmonary angiography
Answer: D. CT pulmonary angiography

Which type of lung sounds are typically heard in a patient with pulmonary edema?

Wheezing
B. Crackles
C. Rhonchi
D. Pleural friction rub
Answer: B. Crackles

A patient with tuberculosis is prescribed isoniazid. What is the most important patient teaching point?

Avoid dairy products
B. Take the medication with meals
C. Monitor for signs of liver toxicity
D. Limit fluid intake
Answer: C. Monitor for signs of liver toxicity

Which of the following is the priority nursing diagnosis for a patient with a tracheostomy?

Impaired physical mobility
B. Risk for infection
C. Ineffective airway clearance
D. Altered nutrition
Answer: C. Ineffective airway clearance

Which acid-base imbalance is commonly seen in patients with respiratory failure?

Metabolic acidosis
B. Metabolic alkalosis
C. Respiratory acidosis
D. Respiratory alkalosis
Answer: C. Respiratory acidosis

What is a common early symptom of lung cancer?

Persistent cough
B. Chest pain
C. Hemoptysis
D. Shortness of breath
Answer: A. Persistent cough

A nurse auscultates diminished breath sounds in the left lower lung field of a postoperative patient. What is the likely cause?

Atelectasis
B. Pneumothorax
C. Bronchitis
D. Pulmonary embolism
Answer: A. Atelectasis

Which of the following is an expected finding in a patient with emphysema?

Barrel-shaped chest
B. Cyanosis
C. Frequent infections
D. Clubbing of the fingers
Answer: A. Barrel-shaped chest

What should the nurse monitor for in a patient with a chest tube?

Continuous bubbling in the water seal chamber
B. Fluctuation in the water seal chamber with respirations
C. Absence of drainage for 24 hours
D. Drainage greater than 100 mL per hour
Answer: B. Fluctuation in the water seal chamber with respirations

Which condition is commonly associated with wheezing?

Pleural effusion
B. Asthma
C. Pneumonia
D. Pulmonary fibrosis
Answer: B. Asthma

What is the priority assessment for a patient receiving oxygen therapy?

Skin integrity
B. Level of consciousness
C. Respiratory rate and effort
D. Nutritional status
Answer: C. Respiratory rate and effort

A patient with cystic fibrosis is at increased risk for which complication?

Pneumothorax
B. Pulmonary hypertension
C. Respiratory infections
D. Pulmonary embolism
Answer: C. Respiratory infections

Which medication is used as a first-line treatment for pulmonary tuberculosis?

Rifampin
B. Amoxicillin
C. Ciprofloxacin
D. Prednisone
Answer: A. Rifampin

What does a SpO2 level below 90% indicate?

Hypoxia
B. Hypercapnia
C. Acidosis
D. Bradycardia
Answer: A. Hypoxia

A patient reports shortness of breath after surgery. What is the nurse’s first action?

Assess oxygen saturation
B. Administer oxygen
C. Notify the provider
D. Position the patient supine
Answer: A. Assess oxygen saturation

What is the primary cause of pneumothorax?

Fluid accumulation in the pleural space
B. Air in the pleural space
C. Infection in the lung tissue
D. Inflammation of the alveoli
Answer: B. Air in the pleural space

What dietary advice is appropriate for a patient with COPD?

Low-calorie, low-fat diet
B. High-protein, high-calorie diet
C. High-fiber diet
D. Low-sodium diet
Answer: B. High-protein, high-calorie diet

What symptom differentiates bronchitis from pneumonia?

Fever
B. Productive cough
C. Rales
D. Chest pain
Answer: C. Rales

Which intervention is most appropriate for a patient with obstructive sleep apnea?

Administer diuretics
B. Use of continuous positive airway pressure (CPAP)
C. Chest physiotherapy
D. Avoiding protein in the diet
Answer: B. Use of continuous positive airway pressure (CPAP)

Which symptom is most characteristic of pleuritis?

Sharp chest pain with breathing
B. Dry cough
C. Wheezing
D. Fever
Answer: A. Sharp chest pain with breathing

Which of the following is a common trigger for asthma?

Alcohol consumption
B. Cold air
C. High salt intake
D. Exercise
Answer: B. Cold air

In patients with COPD, why is it important to limit oxygen flow to 2-3 L/min?

To prevent oxygen toxicity
B. To avoid suppressing the hypoxic drive
C. To conserve oxygen supplies
D. To prevent hyperventilation
Answer: B. To avoid suppressing the hypoxic drive

What is the purpose of pursed-lip breathing in COPD patients?

Increase lung capacity
B. Promote deep breathing
C. Prevent airway collapse
D. Reduce bronchospasm
Answer: C. Prevent airway collapse

What is the most common cause of community-acquired pneumonia?

Staphylococcus aureus
B. Streptococcus pneumoniae
C. Pseudomonas aeruginosa
D. Klebsiella pneumoniae
Answer: B. Streptococcus pneumoniae

 

What is the primary goal of oxygen therapy in a patient with hypoxemia?

Prevent oxygen toxicity
B. Reduce hypercapnia
C. Maintain adequate tissue oxygenation
D. Increase hemoglobin levels
Answer: C. Maintain adequate tissue oxygenation

Which of the following is a key symptom of a pleural effusion?

Dry cough
B. Decreased breath sounds over the affected area
C. Cyanosis
D. Expiratory wheezing
Answer: B. Decreased breath sounds over the affected area

What is the most effective way to prevent ventilator-associated pneumonia (VAP)?

Administer prophylactic antibiotics
B. Perform frequent oral care
C. Keep the patient supine
D. Change ventilator tubing daily
Answer: B. Perform frequent oral care

Which diagnostic test confirms tuberculosis (TB)?

Chest X-ray
B. Sputum culture
C. Mantoux skin test
D. Complete blood count
Answer: B. Sputum culture

Which nursing intervention is most effective for promoting airway clearance in a patient with pneumonia?

Limiting fluid intake
B. Administering antipyretics
C. Encouraging coughing and deep breathing
D. Restricting physical activity
Answer: C. Encouraging coughing and deep breathing

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