NCLEX Integumentary Disorders Practice Exam Questions and Answers

160 Questions and Answers

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Understanding the integumentary system is vital for any nurse preparing for the NCLEX-RN exam. This NCLEX Integumentary Disorders Practice Exam Questions and Answers resource is designed to reinforce your knowledge and test your ability to manage a wide range of skin-related conditions through real exam-style scenarios.

This practice test includes comprehensive, clinically relevant questions covering:

  • Stages and management of pressure ulcers

  • Common inflammatory conditions like eczema and psoriasis

  • Bacterial, viral, and fungal skin infections

  • Burn classifications and emergency care

  • Skin cancers and abnormal lesion identification

  • Autoimmune skin conditions such as lupus erythematosus and scleroderma

Each multiple-choice question is paired with a clear, concise explanation to help you understand not just the correct answer—but why it’s correct. This helps build critical thinking and clinical decision-making skills essential for NCLEX success.

The questions are carefully crafted to mirror NCLEX testing strategies, including prioritization, delegation, patient safety, and nursing process application. Whether you are reviewing integumentary system pathophysiology, preparing for real-world scenarios, or brushing up on patient teaching and pharmacologic interventions, this practice exam will help you strengthen your exam readiness.

It is ideal for nursing students approaching the NCLEX-RN or NCLEX-PN, as well as for those in review courses or clinical prep programs. Use it to track your performance, target weak areas, and build confidence in managing integumentary health challenges effectively.

Sample Questions and Answers

A nurse is assessing a patient with a stage 2 pressure ulcer. Which of the following is the most appropriate description?

Full-thickness tissue loss with exposed bone
B. Partial-thickness skin loss with exposed dermis
C. Full-thickness tissue loss without exposed bone
D. Reddened skin without open wounds

Answer: B. Partial-thickness skin loss with exposed dermis

A patient is admitted with a burn injury to 30% of the body. Which of the following is the priority in the immediate post-burn period?

Pain management
B. Fluid resuscitation
C. Wound debridement
D. Psychological support

Answer: B. Fluid resuscitation

Which of the following is the best indicator of tissue perfusion in a patient with a burn injury?

Blood pressure
B. Urine output
C. Heart rate
D. Respiratory rate

Answer: B. Urine output

A nurse is caring for a patient with a fungal infection of the skin. Which of the following medications is commonly used to treat dermatophyte infections?

Amphotericin B
B. Clotrimazole
C. Acyclovir
D. Vancomycin

Answer: B. Clotrimazole

Which of the following is a common complication of third-degree burns?

Hypothermia
B. Hypervolemia
C. Respiratory distress
D. Hypertension

Answer: A. Hypothermia

A patient with eczema has been prescribed a topical corticosteroid. Which of the following should the nurse monitor for?

Hypokalemia
B. Hyperglycemia
C. Hypotension
D. Bradycardia

Answer: B. Hyperglycemia

The nurse is assessing a patient with shingles. Which area is most likely to be affected by the herpes zoster virus?

Chest and abdomen
B. Lower extremities
C. Upper arms
D. Face and ears

Answer: A. Chest and abdomen

A nurse is educating a patient with psoriasis about the disease process. Which statement by the patient indicates understanding?

“Psoriasis is caused by a viral infection.”
B. “The rash will go away with antibiotics.”
C. “It is a chronic, autoimmune disease.”
D. “Psoriasis can be cured with topical creams.”

Answer: C. “It is a chronic, autoimmune disease.”

A nurse is teaching a patient with acne vulgaris about proper skin care. Which of the following statements is appropriate?

“You should wash your face with hot water to open up your pores.”
B. “You should use oil-based skin products to moisturize your face.”
C. “You should avoid scrubbing your skin aggressively.”
D. “You should apply strong astringents to dry out your skin.”

Answer: C. “You should avoid scrubbing your skin aggressively.”

Which of the following is a characteristic of a basal cell carcinoma?

Irregular, raised border with a central ulcer
B. Flat, brown, or black lesions with irregular borders
C. Raised, scaly lesion with silvery appearance
D. Dark-colored, raised moles that itch

Answer: A. Irregular, raised border with a central ulcer

A nurse is caring for a patient with impetigo. Which of the following is the priority intervention?

Administering antibiotics
B. Keeping the patient isolated from others
C. Applying topical corticosteroids
D. Keeping the affected area moisturized

Answer: A. Administering antibiotics

A patient presents with an erythematous rash, a fever, and fatigue. The patient’s history includes recent exposure to someone with measles. The nurse suspects measles. Which of the following is a classic sign of measles?

Koplik spots
B. Honey-colored crusts
C. Red, raised lesions on the face and neck
D. Scaly, silvery patches

Answer: A. Koplik spots

A nurse is caring for a patient with a severe sunburn. Which of the following interventions should the nurse prioritize?

Apply ice packs to the affected areas
B. Administer analgesics as prescribed
C. Apply corticosteroid cream to the skin
D. Restrict fluid intake

Answer: B. Administer analgesics as prescribed

A nurse is caring for a patient with a stage 3 pressure ulcer. Which of the following is the most important aspect of the plan of care?

Debriding the ulcer
B. Providing adequate nutrition
C. Keeping the ulcer dry and free from infection
D. Using hydrocolloid dressings

Answer: B. Providing adequate nutrition

A nurse is caring for a patient who has been diagnosed with cellulitis. Which of the following is the priority nursing intervention?

Apply warm compresses to the affected area
B. Encourage increased fluid intake
C. Administer oral antibiotics as prescribed
D. Keep the affected area elevated

Answer: C. Administer oral antibiotics as prescribed

A patient with a history of chronic venous insufficiency has developed an ulcer on the lower leg. Which of the following is the most appropriate action to promote healing?

Keep the leg elevated to reduce swelling
B. Apply pressure to the ulcer with a tight bandage
C. Use a heating pad to increase blood flow
D. Massage the area to promote circulation

Answer: A. Keep the leg elevated to reduce swelling

A nurse is caring for a patient with a suspected allergic contact dermatitis. Which of the following should the nurse avoid using on the patient’s skin?

Calamine lotion
B. Petroleum jelly
C. Aloe vera gel
D. Hydrocortisone cream

Answer: B. Petroleum jelly

A patient has been diagnosed with scabies. Which of the following treatments is appropriate?

Oral acyclovir
B. Topical permethrin
C. Topical antifungal cream
D. Oral prednisone

Answer: B. Topical permethrin

A nurse is caring for a patient with a large mole that has irregular borders, asymmetry, and multiple colors. The nurse suspects melanoma. Which of the following is the next step in management?

Perform a biopsy of the mole
B. Apply a topical corticosteroid
C. Monitor the mole for changes
D. Remove the mole surgically

Answer: A. Perform a biopsy of the mole

A nurse is educating a patient on how to prevent pressure ulcers. Which of the following is the most important recommendation?

Reposition the patient at least every 2 hours
B. Use a donut-shaped cushion when sitting
C. Massage bony prominences to improve circulation
D. Keep the patient in one position for long periods

Answer: A. Reposition the patient at least every 2 hours

A patient with a recent burn injury is at risk for infection. Which of the following should the nurse monitor for?

Hypotension
B. Decreased white blood cell count
C. Redness and warmth at the wound site
D. Decreased urine output

Answer: C. Redness and warmth at the wound site

A patient with a deep partial-thickness burn (second-degree) is at risk for hypovolemic shock. Which of the following signs should the nurse prioritize monitoring?

Bradycardia
B. Increased blood pressure
C. Decreased urine output
D. Increased respiratory rate

Answer: C. Decreased urine output

A patient with a history of recurrent cold sores is diagnosed with herpes simplex virus. Which of the following treatments is most appropriate?

Topical antiviral creams
B. Systemic antibiotics
C. Antihistamines
D. Topical corticosteroids

Answer: A. Topical antiviral creams

A nurse is caring for a patient with a dermatological condition. The patient asks about using sunscreen. Which SPF level should the nurse recommend for adequate protection?

SPF 15
B. SPF 30
C. SPF 50
D. SPF 100

Answer: B. SPF 30

A nurse is educating a patient with eczema on proper skin care. Which of the following instructions is most important?

“Apply a thick layer of moisturizer immediately after bathing.”
B. “Avoid using soap, but use water instead.”
C. “Take long, hot showers to relieve itching.”
D. “Wear tight, synthetic fabrics to reduce irritation.”

Answer: A. “Apply a thick layer of moisturizer immediately after bathing.”

A nurse is caring for a patient who has been diagnosed with tinea corporis. Which of the following is the most appropriate treatment?

Topical antifungal medications
B. Topical corticosteroids
C. Oral antibiotics
D. Oral antiviral medications

Answer: A. Topical antifungal medications

A nurse is caring for a patient with atopic dermatitis. Which of the following is the priority in the nursing plan of care?

Apply moisturizers frequently
B. Keep the skin exposed to sunlight
C. Use astringents to dry the skin
D. Limit fluid intake to reduce swelling

Answer: A. Apply moisturizers frequently

A patient with a history of basal cell carcinoma is at increased risk for which of the following?

Squamous cell carcinoma
B. Melanoma
C. Keloid formation
D. Fungal skin infections

Answer: A. Squamous cell carcinoma

A nurse is teaching a patient with a sunburn about the best approach to healing. Which of the following should the nurse emphasize?

Apply ice to the affected areas frequently
B. Take warm baths to soothe the skin
C. Drink plenty of fluids to rehydrate the body
D. Apply a topical corticosteroid cream immediately

Answer: C. Drink plenty of fluids to rehydrate the body

A nurse is caring for a patient with a burn injury. Which of the following is a priority action?

Administer intravenous fluids
B. Apply topical antibiotics
C. Provide pain relief
D. Assess for signs of respiratory distress

Answer: A. Administer intravenous fluids

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