Sample Questions and Answers
Which of the following is the primary target of most psychoactive drugs?
A) Heart
B) Brain
C) Lungs
D) Liver
Answer: B
Which neurotransmitter is most commonly associated with the effects of alcohol?
A) Dopamine
B) Serotonin
C) GABA
D) Acetylcholine
Answer: C
What is the term used to describe the physical and psychological symptoms that occur when a person stops using a substance?
A) Withdrawal
B) Intoxication
C) Tolerance
D) Toxicity
Answer: A
Which of the following best describes the effect of cocaine on the brain?
A) It increases dopamine reuptake.
B) It stimulates serotonin production.
C) It blocks dopamine reuptake.
D) It decreases norepinephrine levels.
Answer: C
Which drug class is primarily used to treat opioid addiction?
A) Antidepressants
B) Benzodiazepines
C) Opioid agonists
D) Stimulants
Answer: C
What is the primary mechanism of action of benzodiazepines?
A) Inhibition of dopamine release
B) Enhancement of GABA activity
C) Blocking serotonin receptors
D) Inhibition of acetylcholine synthesis
Answer: B
Which of the following is a common side effect of chronic alcohol use?
A) Insomnia
B) Weight gain
C) Liver damage
D) Hypertension
Answer: C
Which of the following is a symptom of opioid overdose?
A) Increased heart rate
B) Shallow breathing
C) Hyperactivity
D) Dilated pupils
Answer: B
What is the main goal of pharmacotherapy in addiction treatment?
A) To increase tolerance to the substance
B) To reduce cravings and withdrawal symptoms
C) To enhance the psychoactive effects of the drug
D) To completely eliminate the need for therapy
Answer: B
Which screening tool is most commonly used to assess alcohol use disorders?
A) CAGE Questionnaire
B) PHQ-9
C) DSM-5
D) GAD-7
Answer: A
Which of the following is the legal classification of marijuana in many regions?
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV
Answer: A
Which of the following is a common effect of cannabis use?
A) Increased appetite
B) Increased motor coordination
C) Decreased heart rate
D) Increased alertness
Answer: A
What is the primary purpose of naloxone in opioid overdose situations?
A) To reverse opioid toxicity
B) To enhance opioid effects
C) To reduce alcohol cravings
D) To treat nicotine addiction
Answer: A
Which of the following is the effect of tolerance on drug use?
A) The drug becomes more addictive.
B) The drug loses its potency over time.
C) A person requires more of the drug to achieve the same effect.
D) The drug becomes completely ineffective.
Answer: C
What is the major function of the blood-brain barrier in relation to psychoactive substances?
A) It prevents all drugs from entering the brain.
B) It allows the passage of all substances into the brain.
C) It regulates which substances can cross into the brain.
D) It eliminates waste from the brain.
Answer: C
Which of the following is a long-term consequence of chronic stimulant use?
A) Increased body temperature and heart rate
B) Decreased appetite
C) Impaired decision-making and memory
D) Improved mental clarity
Answer: C
What is the primary risk of combining alcohol with benzodiazepines?
A) Increased risk of withdrawal
B) Decreased sedation
C) Severe respiratory depression
D) Enhanced mood stabilization
Answer: C
Which neurotransmitter is implicated in the effects of nicotine?
A) Norepinephrine
B) GABA
C) Dopamine
D) Serotonin
Answer: C
Which type of drug is methadone?
A) Stimulant
B) Opioid agonist
C) Benzodiazepine
D) Hallucinogen
Answer: B
What is the term for the process by which the body becomes less sensitive to a drug over time?
A) Tolerance
B) Withdrawal
C) Addiction
D) Sensitization
Answer: A
Which of the following is a common side effect of stimulants such as amphetamines?
A) Decreased blood pressure
B) Decreased alertness
C) Increased heart rate
D) Increased appetite
Answer: C
Which of the following best describes the role of pharmacotherapy in the treatment of addiction?
A) It completely cures the addiction.
B) It reduces the likelihood of relapse by managing symptoms.
C) It provides long-term side effects to monitor.
D) It encourages the use of alternative substances.
Answer: B
Which drug is commonly used as a pharmacological treatment for alcohol use disorder?
A) Disulfiram
B) Methadone
C) Cocaine
D) Heroin
Answer: A
Which of the following is NOT a characteristic of withdrawal from benzodiazepines?
A) Seizures
B) Anxiety
C) Increased appetite
D) Insomnia
Answer: C
Which of the following substances is commonly used to manage nicotine addiction?
A) Methadone
B) Buprenorphine
C) Varenicline
D) Naloxone
Answer: C
Which of the following is a typical sign of intoxication with hallucinogens such as LSD?
A) Intense euphoria
B) Impaired memory and judgment
C) Sedation
D) Hallucinations and altered sensory perception
Answer: D
Which of the following is a key component of a comprehensive treatment plan for addiction?
A) Immediate detoxification
B) Addressing the psychological and physiological aspects of addiction
C) Encouraging prolonged substance use
D) Reducing the need for social support
Answer: B
Which drug class is typically used in the treatment of depression in individuals with substance use disorders?
A) Antipsychotics
B) Antidepressants
C) Anticonvulsants
D) Anxiolytics
Answer: B
Which of the following is a common side effect of chronic opioid use?
A) Weight loss
B) Constipation
C) Hypersomnia
D) Memory enhancement
Answer: B
Which of the following is a potential consequence of using psychoactive substances during pregnancy?
A) Increased birth weight
B) Reduced risk of birth defects
C) Fetal alcohol syndrome
D) Increased cognitive development
Answer: C
31. Which of the following is a risk factor for developing substance use disorder?
A) High socioeconomic status
B) Genetic predisposition
C) Strong family support
D) Lack of access to healthcare
Answer: B
32. Which of the following drugs is commonly used in the management of alcohol withdrawal symptoms?
A) Lorazepam
B) Methadone
C) Naltrexone
D) Disulfiram
Answer: A
33. Which of the following is the primary effect of opioids on the brain?
A) Increase serotonin release
B) Block dopamine receptors
C) Activate opioid receptors, leading to pain relief and euphoria
D) Inhibit GABA activity
Answer: C
34. Which of the following is the primary reason why some individuals may become addicted to psychoactive substances?
A) Their social environment encourages drug use
B) They have a genetic predisposition to addiction
C) They lack access to healthcare
D) They are seeking to improve cognitive abilities
Answer: B
35. Which of the following is NOT a symptom of opioid overdose?
A) Decreased respiration
B) Constricted pupils
C) Increased heart rate
D) Loss of consciousness
Answer: C
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