Nursing Pharmacology Chemotherapy Questions and Answers

Sample Questions and Answers

Question 1:

What is the primary mechanism of action for alkylating agents in chemotherapy?
A. Inhibiting DNA synthesis
B. Inducing DNA cross-linking
C. Targeting microtubules
D. Blocking enzyme activity
Answer: B

Question 2:

Which of the following is a common side effect of most chemotherapy drugs?
A. Hyperglycemia
B. Diarrhea
C. Immunosuppression
D. Insomnia
Answer: C

Question 3:

What does the term “adjuvant chemotherapy” refer to?
A. Chemotherapy used alone
B. Chemotherapy given after surgery
C. Chemotherapy given to alleviate symptoms
D. Chemotherapy given in combination with radiation therapy
Answer: B

Question 4:

Which chemotherapeutic drug is classified as an antimetabolite?
A. Cisplatin
B. Methotrexate
C. Paclitaxel
D. Vincristine
Answer: B

Question 5:

What is the dose-limiting toxicity for doxorubicin?
A. Nephrotoxicity
B. Cardiotoxicity
C. Neurotoxicity
D. Hepatotoxicity
Answer: B

Question 6:

Which of the following is a cell cycle-specific chemotherapy agent?
A. Cyclophosphamide
B. 5-Fluorouracil
C. Vinblastine
D. Cisplatin
Answer: C

Question 7:

What is the most common route of administration for chemotherapy drugs?
A. Oral
B. Intramuscular
C. Intravenous
D. Subcutaneous
Answer: C

Question 8:

Which of the following drugs is used to treat nausea and vomiting caused by chemotherapy?
A. Ondansetron
B. Warfarin
C. Metformin
D. Lisinopril
Answer: A

Question 9:

Which chemotherapy agent is associated with peripheral neuropathy as a side effect?
A. Vincristine
B. Doxorubicin
C. Methotrexate
D. Cyclophosphamide
Answer: A

Question 10:

What is the role of leucovorin in combination with methotrexate?
A. Enhance its efficacy
B. Reduce its toxicity
C. Prolong its half-life
D. Prevent drug resistance
Answer: B

Question 11:

Paclitaxel is classified as:
A. An alkylating agent
B. A taxane
C. An antimetabolite
D. A monoclonal antibody
Answer: B

Question 12:

Which chemotherapy drug is known for causing hemorrhagic cystitis?
A. Cisplatin
B. Cyclophosphamide
C. Vincristine
D. Methotrexate
Answer: B

Question 13:

Why is filgrastim often administered to patients undergoing chemotherapy?
A. To increase red blood cell production
B. To stimulate white blood cell production
C. To prevent alopecia
D. To reduce gastrointestinal side effects
Answer: B

Question 14:

The term “neoadjuvant chemotherapy” refers to:
A. Chemotherapy given before surgery
B. Chemotherapy given after surgery
C. Chemotherapy given for palliative care
D. Chemotherapy given to prevent recurrence
Answer: A

Question 15:

Which of the following is a topoisomerase inhibitor?
A. Cisplatin
B. Irinotecan
C. Doxorubicin
D. Methotrexate
Answer: B

Question 16:

What is the main toxicity associated with cisplatin?
A. Neurotoxicity
B. Nephrotoxicity
C. Cardiotoxicity
D. Hepatotoxicity
Answer: B

Question 17:

Which of the following is a common side effect of 5-Fluorouracil?
A. Hypertension
B. Mucositis
C. Myopathy
D. Hypoglycemia
Answer: B

Question 18:

What is the primary target of monoclonal antibodies in chemotherapy?
A. Enzymes involved in metabolism
B. Specific proteins on cancer cells
C. DNA replication machinery
D. Microtubule assembly
Answer: B

Question 19:

Tamoxifen is most commonly used to treat which type of cancer?
A. Lung cancer
B. Breast cancer
C. Colon cancer
D. Pancreatic cancer
Answer: B

Question 20:

Which of the following is a mechanism of resistance to chemotherapy?
A. Increased apoptosis
B. Increased drug efflux pumps
C. Increased drug binding to target proteins
D. Increased immune response
Answer: B

Question 21:

Which of the following chemotherapy drugs is a platinum compound?
A. Doxorubicin
B. Methotrexate
C. Cisplatin
D. Vincristine
Answer: C

Question 22:

Which side effect is most commonly associated with anthracyclines?
A. Pulmonary fibrosis
B. Cardiotoxicity
C. Hemorrhagic cystitis
D. Ototoxicity
Answer: B

Question 23:

Which type of chemotherapy targets the M-phase of the cell cycle?
A. Antimetabolites
B. Alkylating agents
C. Microtubule inhibitors
D. Topoisomerase inhibitors
Answer: C

Question 24:

Which chemotherapy agent is used as a radiosensitizer?
A. Cisplatin
B. Methotrexate
C. Doxorubicin
D. Paclitaxel
Answer: A

Question 25:

What is the main purpose of combination chemotherapy?
A. Reduce costs of treatment
B. Improve efficacy and prevent resistance
C. Limit adverse side effects
D. Minimize treatment duration
Answer: B

Question 26:

What is the term for the lowest point of blood cell counts during chemotherapy?
A. Anemia
B. Leukopenia
C. Nadir
D. Thrombocytopenia
Answer: C

Question 27:

Bevacizumab inhibits which process to combat tumor growth?
A. DNA synthesis
B. Angiogenesis
C. Apoptosis
D. Protein synthesis
Answer: B

Question 28:

What is the most effective intervention for preventing chemotherapy-induced alopecia?
A. Scalp cooling
B. Topical corticosteroids
C. Regular haircuts
D. Avoiding sun exposure
Answer: A

Question 29:

What is the function of dexrazoxane in chemotherapy?
A. Enhance drug efficacy
B. Protect the heart from toxicity
C. Boost immune response
D. Reduce nausea
Answer: B

Question 30:

Which chemotherapeutic drug is a pyrimidine analog?
A. Cisplatin
B. Methotrexate
C. 5-Fluorouracil
D. Vinblastine
Answer: C