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NCLEX Endocrine System Disorders Exam Questions and Answers

150 Questions and Answers

$6.99

Mastering the complexities of the endocrine system is essential for every aspiring nurse. This NCLEX Endocrine System Disorders Exam Questions and Answers resource offers a targeted, in-depth review to help nursing students and candidates confidently prepare for questions related to hormonal regulation, endocrine glands, and associated disorders on the NCLEX-RN and NCLEX-PN exams.

This expertly designed practice exam includes a wide range of multiple-choice questions that test both fundamental knowledge and clinical application. Topics covered include:

  • Functions of the endocrine glands (pituitary, thyroid, adrenal, pancreas, etc.)

  • Disorders such as diabetes mellitus, Addison’s disease, Cushing’s syndrome, hypothyroidism, hyperthyroidism, and more

  • Hormonal imbalances and their clinical manifestations

  • Nursing assessment, diagnostic procedures, and lab interpretation

  • Patient education and pharmacological interventions, including insulin therapy and corticosteroids

  • Crisis management and prioritization in endocrine emergencies (e.g., diabetic ketoacidosis, thyroid storm)

Each question is followed by a detailed explanation to reinforce core concepts, develop clinical reasoning skills, and support a deeper understanding of nursing responsibilities in endocrine care.

This NCLEX practice exam is ideal for identifying knowledge gaps, refining test-taking strategies, and building confidence in handling high-stakes exam scenarios. Use it to sharpen your knowledge and ensure readiness for all endocrine-related NCLEX questions.

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Sample Questions and Answers

  • Which of the following is a classic symptom of hyperthyroidism?
    A. Bradycardia
    B. Cold intolerance
    C. Heat intolerance
    D. Weight gain
    Answer: C. Heat intolerance
  • Which hormone is secreted by the adrenal cortex?
    A. Insulin
    B. Glucagon
    C. Cortisol
    D. Antidiuretic hormone
    Answer: C. Cortisol
  • A patient with diabetes insipidus will typically present with which symptom?
    A. Polyuria
    B. Oliguria
    C. Hyperglycemia
    D. Hypertension
    Answer: A. Polyuria
  • Which laboratory finding is indicative of hypothyroidism?
    A. Elevated T3 and T4
    B. Elevated TSH
    C. Low TSH
    D. Low blood calcium
    Answer: B. Elevated TSH
  • Which endocrine disorder is caused by an excess of growth hormone in adults?
    A. Cushing’s syndrome
    B. Addison’s disease
    C. Acromegaly
    D. Gigantism
    Answer: C. Acromegaly
  • What is the primary treatment for myxedema coma?
    A. Insulin administration
    B. Intravenous levothyroxine
    C. Oral corticosteroids
    D. Antithyroid medications
    Answer: B. Intravenous levothyroxine
  • What is the hallmark sign of pheochromocytoma?
    A. Persistent hypotension
    B. Severe hypertension
    C. Polyuria and polydipsia
    D. Hypoglycemia
    Answer: B. Severe hypertension
  • Which condition is characterized by moon face, buffalo hump, and central obesity?
    A. Cushing’s syndrome
    B. Graves’ disease
    C. Addison’s disease
    D. Diabetes insipidus
    Answer: A. Cushing’s syndrome
  • A client with SIADH is likely to have which electrolyte imbalance?
    A. Hypernatremia
    B. Hyponatremia
    C. Hypercalcemia
    D. Hypokalemia
    Answer: B. Hyponatremia
  • Which test is used to diagnose diabetes mellitus?
    A. TSH levels
    B. HbA1c test
    C. ACTH stimulation test
    D. Serum calcium test
    Answer: B. HbA1c test
  • Which medication is typically prescribed for hyperthyroidism?
    A. Levothyroxine
    B. Methimazole
    C. Prednisone
    D. Calcitonin
    Answer: B. Methimazole
  • Which symptom is commonly associated with Addison’s disease?
    A. Hyperpigmentation
    B. Hypertension
    C. Hypernatremia
    D. Tachycardia
    Answer: A. Hyperpigmentation
  • What is a priority nursing intervention for a patient in thyroid storm?
    A. Administer aspirin for fever control
    B. Administer IV fluids and beta-blockers
    C. Administer levothyroxine
    D. Encourage oral fluids
    Answer: B. Administer IV fluids and beta-blockers
  • What dietary advice is important for a client with hypoparathyroidism?
    A. Avoid dairy products
    B. Increase calcium-rich foods
    C. Decrease protein intake
    D. Increase sodium-rich foods
    Answer: B. Increase calcium-rich foods
  • Which lab value is critical to monitor for a patient receiving insulin therapy?
    A. Sodium
    B. Potassium
    C. Calcium
    D. Hemoglobin
    Answer: B. Potassium
  • Which is a complication of untreated diabetes mellitus?
    A. Hepatic encephalopathy
    B. Diabetic ketoacidosis (DKA)
    C. Hyperthyroidism
    D. Cushing’s syndrome
    Answer: B. Diabetic ketoacidosis (DKA)
  • What is the primary cause of hyperparathyroidism?
    A. Hypocalcemia
    B. Adenoma of the parathyroid gland
    C. Vitamin D deficiency
    D. Chronic renal failure
    Answer: B. Adenoma of the parathyroid gland
  • A client with Cushing’s syndrome is at increased risk for which condition?
    A. Osteoporosis
    B. Hypotension
    C. Hypoglycemia
    D. Hyperkalemia
    Answer: A. Osteoporosis
  • What symptom is most concerning in a patient with Graves’ disease?
    A. Anxiety
    B. Exophthalmos
    C. Tachycardia
    D. Thyroid storm
    Answer: D. Thyroid storm
  • Which disorder involves an overproduction of ADH?
    A. SIADH
    B. Diabetes mellitus
    C. Diabetes insipidus
    D. Addison’s disease
    Answer: A. SIADH
  • Which is the preferred insulin for an emergency diabetic ketoacidosis (DKA)?
    A. NPH insulin
    B. Regular insulin
    C. Glargine insulin
    D. Detemir insulin
    Answer: B. Regular insulin
  • A priority for a patient with hypoglycemia is:
    A. Administer IV fluids
    B. Provide a carbohydrate-rich snack
    C. Check blood pressure
    D. Administer glucagon only if symptoms worsen
    Answer: B. Provide a carbohydrate-rich snack
  • Which condition is associated with a goiter?
    A. Addison’s disease
    B. Hyperthyroidism
    C. Diabetes insipidus
    D. Cushing’s syndrome
    Answer: B. Hyperthyroidism
  • What is the most important complication to monitor for after thyroidectomy?
    A. Hypertension
    B. Hypocalcemia
    C. Hyperglycemia
    D. Hyponatremia
    Answer: B. Hypocalcemia
  • Which test assesses long-term blood glucose control?
    A. Fasting blood glucose test
    B. Oral glucose tolerance test
    C. HbA1c test
    D. Random plasma glucose
    Answer: C. HbA1c test
  • Which electrolyte disturbance is associated with adrenal crisis?
    A. Hyperkalemia
    B. Hypokalemia
    C. Hypernatremia
    D. Hypercalcemia
    Answer: A. Hyperkalemia
  • Which is a late sign of hypoglycemia?
    A. Diaphoresis
    B. Shakiness
    C. Seizures
    D. Hunger
    Answer: C. Seizures
  • Which intervention is most important in managing a patient with diabetic ketoacidosis?
    A. Administering potassium supplements
    B. Initiating IV insulin therapy
    C. Providing oxygen therapy
    D. Administering corticosteroids
    Answer: B. Initiating IV insulin therapy
  • Which symptom is typical in hypothyroidism?
    A. Tachycardia
    B. Hair thinning
    C. Weight loss
    D. Nervousness
    Answer: B. Hair thinning
  • Which is a risk factor for type 2 diabetes?
    A. Being underweight
    B. Autoimmune conditions
    C. Obesity
    D. Hyperthyroidism
    Answer: C. Obesity

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