Sample Questions and Answers
What is the primary action of NSAIDs like ibuprofen?
A) Increase bone density
B) Reduce inflammation and pain
C) Stimulate muscle growth
D) Promote cartilage repair
Answer: B) Reduce inflammation and pain
Which of the following drugs is commonly prescribed to treat osteoporosis?
A) Alendronate
B) Methotrexate
C) Diazepam
D) Ibuprofen
Answer: A) Alendronate
What is the mechanism of action for bisphosphonates?
A) Inhibits osteoclast activity
B) Stimulates osteoblast production
C) Blocks calcium absorption
D) Promotes vitamin D synthesis
Answer: A) Inhibits osteoclast activity
Methotrexate is commonly used to treat which condition?
A) Osteoporosis
B) Rheumatoid arthritis
C) Osteoarthritis
D) Muscle spasms
Answer: B) Rheumatoid arthritis
Which muscle relaxant is often used to treat acute muscle spasms?
A) Baclofen
B) Aspirin
C) Prednisone
D) Alendronate
Answer: A) Baclofen
Which drug is considered a first-line treatment for gout?
A) Colchicine
B) Allopurinol
C) Prednisone
D) Methotrexate
Answer: B) Allopurinol
What is the primary adverse effect of corticosteroids used for musculoskeletal disorders?
A) Increased bone density
B) Muscle hypertrophy
C) Osteoporosis
D) Reduced inflammation
Answer: C) Osteoporosis
Which medication class is used to prevent fractures in patients with osteoporosis?
A) Beta-blockers
B) Bisphosphonates
C) NSAIDs
D) Anticholinergics
Answer: B) Bisphosphonates
Raloxifene is classified as a:
A) Selective estrogen receptor modulator (SERM)
B) Bisphosphonate
C) Corticosteroid
D) Muscle relaxant
Answer: A) Selective estrogen receptor modulator (SERM)
What is the common side effect of colchicine?
A) Constipation
B) Diarrhea
C) Hypertension
D) Skin rash
Answer: B) Diarrhea
Which drug is often used to treat severe rheumatoid arthritis?
A) Methotrexate
B) Ibuprofen
C) Calcium carbonate
D) Acetaminophen
Answer: A) Methotrexate
Teriparatide is used for:
A) Increasing bone formation
B) Treating muscle spasms
C) Pain management in arthritis
D) Reducing inflammation
Answer: A) Increasing bone formation
Which drug reduces uric acid levels in gout patients?
A) Allopurinol
B) Colchicine
C) Ibuprofen
D) Baclofen
Answer: A) Allopurinol
Which NSAID has the lowest risk of gastrointestinal side effects?
A) Naproxen
B) Celecoxib
C) Ibuprofen
D) Indomethacin
Answer: B) Celecoxib
Denosumab works by:
A) Inhibiting RANK ligand activity
B) Stimulating osteoclasts
C) Enhancing calcium excretion
D) Blocking prostaglandins
Answer: A) Inhibiting RANK ligand activity
Which drug is used as a rescue therapy for acute gout?
A) Indomethacin
B) Probenecid
C) Alendronate
D) Raloxifene
Answer: A) Indomethacin
What is the primary therapeutic use of cyclobenzaprine?
A) Treating chronic inflammation
B) Managing muscle spasms
C) Treating gout
D) Increasing bone mass
Answer: B) Managing muscle spasms
What is the most common adverse effect of bisphosphonates?
A) Joint pain
B) Gastrointestinal discomfort
C) Skin rash
D) Hypertension
Answer: B) Gastrointestinal discomfort
Which of the following is a calcitonin-based drug used in osteoporosis?
A) Teriparatide
B) Calcitonin-salmon
C) Risedronate
D) Prednisone
Answer: B) Calcitonin-salmon
What is the primary purpose of vitamin D supplementation in musculoskeletal health?
A) Increase muscle tone
B) Enhance calcium absorption
C) Reduce inflammation
D) Inhibit osteoclasts
Answer: B) Enhance calcium absorption
Which drug class is used to delay the progression of rheumatoid arthritis?
A) DMARDs
B) NSAIDs
C) Opioids
D) Corticosteroids
Answer: A) DMARDs
Probenecid works by:
A) Increasing uric acid excretion
B) Reducing inflammation
C) Blocking pain signals
D) Enhancing calcium absorption
Answer: A) Increasing uric acid excretion
Which of the following is a synthetic parathyroid hormone?
A) Risedronate
B) Teriparatide
C) Denosumab
D) Methotrexate
Answer: B) Teriparatide
The main action of glucocorticoids in musculoskeletal disorders is to:
A) Build muscle mass
B) Suppress inflammation
C) Promote bone growth
D) Increase joint flexibility
Answer: B) Suppress inflammation
A common side effect of long-term corticosteroid use is:
A) Hypertension
B) Hyperkalemia
C) Adrenal suppression
D) Increased uric acid levels
Answer: C) Adrenal suppression
Which of these is a TNF inhibitor used in rheumatoid arthritis?
A) Etanercept
B) Methotrexate
C) Colchicine
D) Alendronate
Answer: A) Etanercept
Calcium supplements are often paired with which vitamin for improved absorption?
A) Vitamin A
B) Vitamin B12
C) Vitamin D
D) Vitamin C
Answer: C) Vitamin D
Which of the following drugs is an anti-inflammatory agent used for ankylosing spondylitis?
A) Indomethacin
B) Allopurinol
C) Baclofen
D) Methotrexate
Answer: A) Indomethacin
Which medication is used to prevent bone loss during long-term glucocorticoid therapy?
A) Raloxifene
B) Denosumab
C) Alendronate
D) Calcitonin
Answer: C) Alendronate
Which drug is administered via subcutaneous injection for osteoporosis?
A) Denosumab
B) Risedronate
C) Naproxen
D) Methotrexate
Answer: A) Denosumab
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