Sample Questions and Answers
Which class of drugs is commonly used to treat peptic ulcers?
A) Antihistamines
B) Proton pump inhibitors (PPIs)
C) Beta-blockers
D) Anticholinergics
Answer: B) Proton pump inhibitors (PPIs)
Which of the following is an adverse effect of proton pump inhibitors (PPIs)?
A) Constipation
B) Hypocalcemia
C) Diarrhea
D) Osteoporosis
Answer: D) Osteoporosis
What is the mechanism of action of H2-receptor antagonists?
A) Inhibit gastric acid secretion by blocking histamine receptors
B) Increase gastric acid secretion
C) Neutralize stomach acid
D) Increase motility in the stomach
Answer: A) Inhibit gastric acid secretion by blocking histamine receptors
Which of the following drugs is used to treat irritable bowel syndrome (IBS) with diarrhea (IBS-D)?
A) Alosetron
B) Metoclopramide
C) Ranitidine
D) Omeprazole
Answer: A) Alosetron
Which drug class is most commonly used to relieve heartburn and acid reflux?
A) Proton pump inhibitors
B) H2 blockers
C) Antacids
D) Antispasmodics
Answer: C) Antacids
Which medication is used to treat constipation by increasing water content in the stool?
A) Loperamide
B) Lactulose
C) Misoprostol
D) Dicyclomine
Answer: B) Lactulose
Which of the following is a common side effect of opioid-induced constipation?
A) Diarrhea
B) Nausea
C) Bloating
D) Drowsiness
Answer: C) Bloating
What is the primary action of antiemetics such as ondansetron?
A) Suppress nausea and vomiting
B) Promote digestion
C) Increase appetite
D) Relieve abdominal pain
Answer: A) Suppress nausea and vomiting
Which of the following drugs is used to prevent gastric ulcers associated with NSAID use?
A) Omeprazole
B) Misoprostol
C) Dicyclomine
D) Esomeprazole
Answer: B) Misoprostol
Which of the following is a common side effect of metoclopramide (Reglan)?
A) Sedation
B) Diarrhea
C) Tardive dyskinesia
D) Constipation
Answer: C) Tardive dyskinesia
Which drug class is used to reduce gastric acid production and treat gastroesophageal reflux disease (GERD)?
A) Antacids
B) Proton pump inhibitors
C) Laxatives
D) Anticholinergics
Answer: B) Proton pump inhibitors
Which of the following medications can be used to treat nausea associated with chemotherapy?
A) Fexofenadine
B) Ondansetron
C) Diphenhydramine
D) Ranitidine
Answer: B) Ondansetron
Which of the following is a first-line treatment for mild to moderate GERD?
A) H2 blockers
B) Prokinetic agents
C) Antacids
D) Proton pump inhibitors
Answer: A) H2 blockers
Which class of drugs is used to treat diarrhea by slowing down bowel motility?
A) Antidiarrheals
B) Antacids
C) Laxatives
D) Antispasmodics
Answer: A) Antidiarrheals
Which of the following drugs is commonly used to treat Helicobacter pylori infection?
A) Tetracycline
B) Clarithromycin
C) Azithromycin
D) Loperamide
Answer: B) Clarithromycin
What is the mechanism of action of sucralfate in treating ulcers?
A) Increases gastric acid production
B) Forms a protective barrier over ulcers
C) Inhibits histamine release
D) Promotes gastric motility
Answer: B) Forms a protective barrier over ulcers
Which of the following is an adverse effect of calcium-based antacids?
A) Diarrhea
B) Constipation
C) Headache
D) Vomiting
Answer: B) Constipation
Which class of drugs is used to manage inflammatory bowel disease (IBD)?
A) Corticosteroids
B) Proton pump inhibitors
C) Antacids
D) Antidiarrheals
Answer: A) Corticosteroids
Which of the following medications is used to treat Helicobacter pylori infection in combination with other drugs?
A) Omeprazole
B) Methylprednisolone
C) Metoclopramide
D) Amoxicillin
Answer: D) Amoxicillin
Which of the following drugs is an antiemetic used for motion sickness prevention?
A) Diphenhydramine
B) Diphenoxylate
C) Dicyclomine
D) Atropine
Answer: A) Diphenhydramine
Which of the following is a contraindication for the use of magnesium-containing antacids?
A) Chronic kidney disease
B) Hypothyroidism
C) Asthma
D) Hypertension
Answer: A) Chronic kidney disease
What is the main action of antispasmodic drugs such as dicyclomine?
A) Increase gastrointestinal motility
B) Relieve abdominal cramps by relaxing smooth muscle
C) Inhibit gastric acid production
D) Promote digestion
Answer: B) Relieve abdominal cramps by relaxing smooth muscle
Which medication is commonly used to treat chronic constipation in patients who do not respond to other treatments?
A) Polyethylene glycol
B) Bisacodyl
C) Linaclotide
D) Sodium bicarbonate
Answer: C) Linaclotide
Which of the following drugs can be used to treat Crohn’s disease?
A) Metronidazole
B) Prochlorperazine
C) Ranitidine
D) Omeprazole
Answer: A) Metronidazole
Which of the following medications is considered a prokinetic agent for increasing gastric motility?
A) Erythromycin
B) Domperidone
C) Simethicone
D) Tetracycline
Answer: B) Domperidone
Which of the following drugs is used to treat nausea associated with gastroparesis?
A) Metoclopramide
B) Diphenhydramine
C) Simethicone
D) Famotidine
Answer: A) Metoclopramide
What is a common side effect of magnesium-based antacids?
A) Diarrhea
B) Constipation
C) Headache
D) Increased heart rate
Answer: A) Diarrhea
Which drug class is used to treat the symptoms of GERD by increasing gastric emptying?
A) Prokinetic agents
B) Proton pump inhibitors
C) Antacids
D) H2 antagonists
Answer: A) Prokinetic agents
Which of the following is a potential side effect of long-term use of proton pump inhibitors (PPIs)?
A) Iron deficiency anemia
B) Hyperkalemia
C) Increased risk of C. difficile infection
D) Hypoglycemia
Answer: C) Increased risk of C. difficile infection
Which of the following drugs is a bile acid sequestrant used to treat diarrhea in patients with bile acid malabsorption?
A) Cholestyramine
B) Diphenoxylate
C) Loperamide
D) Tincture of opium
Answer: A) Cholestyramine
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